Sitepoint tries to figure out how well the Web2.0 works for blind people.

Basically, no US gov website, and none that loves blind people, will be able to implement a AJAX-only site – a noscript verson will have to be available. And this stems from the fact that it’s too hard to make the various screenreaders act in a standard way in response to changes to the document. Which sounds to me to be a perfect problem for World Wide Web Consortium standardisation.